Disease of the digestive system: duodenal ulcer. I.

Disease of the digestive system: duodenal ulcer. I.

Duodenal ulcer continues to be a common disorder in Britain. It still shows a predominance in males, though there is a suggestion that the difference in incidence between the two sexes may not be as great as it was 20 years ago. Reliable data on the overall incidence of peptic ulceration is understandably difficult to acquire in view of the very variable severity and natural course of the disea...

Current Practice DISEASE OF THE DIGESTIVE SYSTEM Perforated Peptic Ulcer

Perforations of peptic ulcers account for between 5 % and 8% of abdominal conditions submitted to urgent laparotomy. The general practitioner may see less than one case a year even though in an average-sized practice he has many patients with peptic ulcers. This relative rarity of the complication of perforation in the experience of the individual practitioner does not often lead to difficulty ...

Duodenal ulcer in sickle cell disease.

Pathogenesis of duodenal ulcer disease: the rest of the story.

Although several duodenal ulcer disease-specific abnormalities in gastric function have been described (e.g. exaggerated gastrin releasing peptide-stimulated acid secretion and an abnormal sensitivity of the parietal cells to gastrin), none has withstood careful examination. We describe here the critical nature of the duodenal acid load in precipitating and washing out bile salts, which inhibit...

Duodenal Ulcer

hardly possible, but all this has been changed by the aggression of surgery in the field of the physician; happily changed, for though postmortem records of duodenal ulcers were common enough it was not until 1883 that Chvostec for the first time made a diagnosis verified at autopsy. Cordivilla of Bologna inaugurated the surgery of chronic duodenal ulcer in 1893 when he successfully operated on...